Tag : inflammation

the value of a balanced diet against Covid-19

November 21, 2021 / Blog

Covid-19 is coming back and the number of cases in many countries around the world are going through the roof.

Today, we need to remember that COVID-19 is related to inflammation and chronic diseases.

The virus causes acute inflammation and chronic inflammation is linked to chronic (or non-communicable) diseases (NCDs). Our group has been working actively on this link and we have published a number of papers.

The anti-inflammatory properties of apples, cider and apple by-products

August 31, 2021 / Blog

Apple industry produces a number of products (e.g. apples, cider etc) with strong anti-inflammatory properties. The evaluation of these activities against inflammation and chronic diseases is the focus of our group.

Antithrombotic and antiplatelet activity of an organometallic rhodium(I) complex incorporating a substituted thieno‐[2,3‐d]‐pyrimidine ligand: Synthesis, structural characterization, and molecular docking calculations

February 22, 2021 / Blog

The synthesis and spectroscopic characterization of the rhodium(I) complex 1 incorporating a substituted thienopyrimidine ligand (tpc) was reported. The solid‐state structures of tpc and 1 were determined, for the first time, by single‐crystal X‐ray diffraction. The biological evaluation of the new compounds (tpc and 1) towards the PAF‐induced aggregation in both WRPs and human platelets (hPRPs) showed that complex 1 proved to be a very potent antiplatelet and antithrombotic agent, showing better efficiency than that of the free ligand.

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

February 4, 2021 / Blog

Antiplatelet therapies are discussed with a view to primary prevention of CVD by the clinical reduction of platelet reactivity and inflammation. Current antiplatelet therapies are effective in reducing cardiovascular risk but increase bleeding risk. Novel therapeutic antiplatelet approaches beyond current pharmacological modalities that do not increase the risk of bleeding require further investigation. There is potential for specifically designed nutraceuticals that may become safer alternatives to pharmacological antiplatelet agents for the primary prevention of CVD but there is serious concern over their efficacy and regulation, which requires considerably more research.

Micronutrients, Phytochemicals, the Mediterranean Diet and Covid-19

January 31, 2021 / Blog

The intra- and inter-relationships of Covid-19, inflammation, nutrition, the Mediterranean Diet and thrombosis.
Platelet aggregation as caused by covid-19 related inflammation and the protective role of diet against thrombosis and covid-19.